Introduction Drug discovery and development is an elaborate and lengthy process, and researchers are constantly seeking innovative tools to unravel the complexities of human biology further and accelerate
In higher eukaryotes, multiple transcript isoforms can originate from a single gene, diversifying the transcriptome and, consequently, the proteome. Transcript isoforms occur due to variations in transcription initiation, splicing, and
RNA therapeutics are a rapidly expanding category of drugs based on RNA with great potential against systemic diseases, such as cancer or infectious diseases. They offer incredible advantages: precision,
RNA therapeutics are a rapidly expanding category of drugs based on RNA molecules aimed at treating or preventing diseases. Recent clinical success and primarily the breakthrough of a series of
Blood is a highly informative, easily accessible, and minimally invasive sample type routinely used for diagnostic purposes and in clinical research to study pathological and physiological conditions and the
While protocols to generate Next Generation Sequencing (NGS) libraries for RNA sequencing (RNA-Seq) have been highly optimized over the past decade, the conversion of RNA to cDNA remains a limiting
Gene expression is the process by which information from a gene is synthesized into a product, RNA and consequently in proteins. The genes that are expressed, known as the genotype,
As the experts in RNA-Seq, we get this question very frequently. In fact, it is a tricky question to answer with confidence. One of the reasons is that RNA-Seq consists
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